Our Therapeutic Expertise in CNS Clinical Trials and Research

Worldwide Clinical Trials’ experience as a Central Nervous System (CNS) CRO providing clinical research is unrivaled. From psychiatry and neurology to analgesia and addiction drug development, our expertise spans translational medicine, registry and peri-approval studies with pharmaco-economic intent. Whether your compound is an original small molecule or bioequivalent generic, injectable large molecule or biosimilar – our Central Nervous System experts are true specialists. At Worldwide Clinical Trials we know a clinical trial is only as good as the data gathered. That’s why our industry-leading rater services from our Clinical Assessment Technologies (CAT) group is fully integrated with the study team and systems.

The Central Nervous System (CNS) franchise at Worldwide is organized into the following sub-therapeutic areas and most studied indications including:


  • Neurodegenerative Disorders (Alzheimer’s Disease, Frontotemporal Dementia, Mild Cognitive Impairment, Traumatic Brain Injury, and Parkinson’s Disease)
  • Autoimmune Neurological Disorders (Multiple Sclerosis)
  • Movement Disorders
  • Neuromuscular Disorders (Disease of Peripheral Nerve, Neuromuscular Junction and Muscle)
  • Epilepsy and Seizure Disorders
  • Sleep Disorders
  • Pain Syndromes (Postoperative Neuropathic Pain, Postherapetic Neuralgia, Breakthrough Episodic Pain, Low Back Pain, Diabetic Neuropathy, Nerve Trauma and Migraines)

Questions about our CNS expertise?

Alzheimer’s Disease and Cognition

  • Mild to Moderate Alzheimer’s Disease
  • Moderate to Severe Alzheimer’s Disease
  • Frontotemporal Dementia
  • Mild Cognitive Impairment
  • Traumatic Brain Injury

Pain Management and Analgesia

  • Breakthrough Cancer Pain
  • Diabetic Neuropathic Pain
  • Lower Back Pain
  • Neuropathic Pain
  • Migraine
  • Osteoarthritic Pain
  • Post-Herpetic Neuralgia
  • Post-Operative Pain


  • Addiction/Drug Dependencies | Opioid Dependence
  • Attention Deficit Hyperactivity Disorder (ADHD) – pediatric and adult
  • Bipolar Disorder
  • Generalized Anxiety Disorder
  • Major Depressive Disorder
  • Schizophrenia (acute, chronic, negative symptoms, cognition)
  • Smoking Cessation

CNS Rare Diseases

  • All CNS Rare/Orphan Diseases