Glioblastoma multiforme (GBM) is a complex indication that has not seen any new approved therapies in well over a decade. The aggressive nature of the disease creates operational and ethical challenges for therapeutic development. Recent innovations are opening new opportunities in translational research for treatment of GBM, and Worldwide Clinical Trials has increased its commitment to supporting oncology research. In this brief video, Alaeddin Homsi, MS, BS, Executive Director for Project Management in Oncology and Hematology, discusses our recent work in GBM studies.