Motivating Patients and Maintaining Rigor in Cardiovascular Clinical Trials

Cardiovascular research can feel like a “numbers game” from design and recruitment to analysis. Worldwide brings the experience, decisiveness and tailored solutions your program needs.

Dedicated cardiovascular teams, 30 years and counting

Worldwide wins the numbers game. We have more than three decades of experience in cardiovascular research, a presence in more than 60 countries, and extensive global trial experience in all phases of research—even involving more than 26,000 patients in a single trial. Yet every single program receives the attention and care of a dedicated team, enabling us to act quickly and effectively in close collaboration with key industry partners. 

Monika Iten, PhD

Vice President Project Management, Cardiovascular

Monika Iten, PhD, is Vice President of Project Management for Cardiovascular at Worldwide Clinical Trials. With more than 18 years of industry experience in clinical operations, performance management, and marketing, she has overseen the successful execution of large-scale, global clinical trials in cardiovascular and metabolic indications. Dr. Iten’s talent for managing complex teams has had a positive impact on team performance, leading in turn to exceptional delivery of results to our customers.

Cultivating cardiovascular success stories one patient—and study—at a time

Cardiovascular trials often require teamwide dedication to a broad scope and a patient, detail-oriented operational approach. At Worldwide, we believe each study relies on the commitment of the individuals involved. Find out how this comes through in everything we do.

Extensive cardiovascular outcomes trial and adjudication experience

Our experience executing large cardiovascular trials has resulted in irreplaceable expertise: a solid understanding of the events, treatment, and outcomes of interest. These studies require event adjudication and close collaboration with Clinical Events Committees (CECs).

A different approach to recruitment & retention

Worldwide can do more than screen patients for inclusion and exclusion criteria. Using emerging predictive analytics technology, we identify the study subjects most likely to comply with the protocol and stay the course of the trial.

Cost-effectiveness through smart planning

Smart screening and high compliance rates reduce enrollment costs. Paired with thoughtful statistical analysis plans and early leading signals for rapid identification of struggling products, we offer shorter trials for patients and faster decision-making guidance for sponsors.

Respectful, people-focused study design

Worldwide minimizes attrition and improves statistical validity by anticipating the pain points most likely to cause attrition. We then proactively work to alleviate those concerns, honoring patients’ time and commitment through compressed timelines and reduced study burden.

Cardiovascular Experience

  • Acute Coronary Syndrome (ACS)
  • Angina
  • Anticoagulation
  • Atherosclerosis
  • Atrial Fibrillation
  • Cardiac Arrhythmias
  • Coronary Artery Disease (CAD)
  • Heart Failure
  • Hypertension
  • Ischemic Heart Disease
  • Myocardial Infarction
  • Pulmonary Arterial Hypertension (PAH)
  • Restenosis
  • Stroke/Cerebrovascular Disease – Prevention
  • Thrombosis

Cardiovascular Resources