Bringing Rigor and Structure to Pain & Addiction Research

Complex study requirements and a lack of validated biomarkers make this crowded research space a logistical minefield. Worldwide offers breakthrough solutions to make this intractable indication less painful to study


Worldwide is a leader in best practice development for pain and addiction research.  Our physicians and scientists understand the specific therapeutic and methodological challenges in analgesic research, which helps us offer creative study designs and thoughtful protection of outcome measures coupled with operational expertise.



Barry has worked in all phases of drug development over the course of his 20+ year career, with the last 10 years focused upon clinical project management. He has spent most of his career in the CNS field, leading study teams in neuropathic pain, migraine, substance-use disorders, and CNS rare disorders. Prior to joining Worldwide, Barry worked for several venture-stage biotech companies, leading teams in migraine and insomnia research. Now he puts his expertise to use for companies of all sizes through his Worldwide consulting work.



With 25 years of experience, Lisa has overseen projects ranging from small, complex Phase I and Phase II studies to global Phase III, IV, and expanded access trials with adult, geriatric, and pediatric populations. Lisa oversees neuroscience programs and personnel, as well as developing processes and tools for high-quality project delivery. She provides operational oversight for Worldwide’s neuroscience portfolio, line management to Global Project Leads, and supports corporate and process improvement initiatives. Her areas of expertise include psychiatric (schizophrenia, depression, bipolar, anxiety, and ADHD), analgesic (post-operative, osteoarthritic and neuropathic), and neurologic (Parkinson’s disease, restless leg syndrome, and Alzheimer’s disease).



Christine Moore, Ph.D., specializes in pain management and supportive care. Prior to coming to Worldwide, she served as a medical science liaison, a vice president of clinical development, and a senior director of rater training services. She also serves as a resource for the neuroscience therapeutic area and the disease state of Attention Deficit Hyperactivity Disorder (ADHD). Christine has extensive experience in study initiation, clinical trial execution, and the provision of scientific and process expertise relating to the management of a compound. Christine managed scientific affairs and medical writing, contributing medical and scientific input into the design of clinical protocols and study documents. Christine is also credited with a multiple published manuscripts, presentations, and abstracts across various therapeutic spaces.

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Making sure your program can see the forest and the trees 

In pain & addiction research, rigorous attention to the details is incredibly important—but so is the practical translation of those details to a big-picture solution. Worldwide—the cure for the common CRO—embraces this complexity and connectivity. 

Neuroscience Experience

Worldwide leads the way in best practice development for pain and addiction research. We have seen it all, which helps us offer the right blend of tried-and-true logistics, creative study designs, and thoughtful outcomes measures to augment objectivity in this otherwise nebulous field of research.

Worldwide was founded to help improve research for neurology patients. Decades later, we’ve done it all, working on a dizzying number of compounds and indications in every phase. Now Worldwide is one of the few full-service CROs that provides integrated rater training, scale management, bespoke assessment development, and a broad range of other highly specialized consulting services in addition to our top-notch global network of study execution experts.

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Our Cognitive Task Force and scale development work speak volumes about our commitment to Alzheimer’s and dementia research. At Worldwide, we design and execute rigorous, compassionate studies we’d be happy to have our own family and friends take part in, carefully protecting the patient experience and maintaining compelling data integrity to get products to market even in this competitive research space.

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Rare neurological diseases each have unique hurdles for developing compelling outcomes assessments that can demonstrate efficacy with small patient populations. Worldwide is a leader in rare disease recruitment, novel endpoint development, and innovative study designs. We deliver specialty studies that apply our overarching knowledge in neurological conditions and rare diseases to thoughtful study designs, respecting patient communities and generating the data sponsors need to advance their compound to market.

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A crowded research space makes it difficult to weed the subjectivity out of the science—which demands a CRO with psychiatry know-how from the ground up and the top down. Our proven track record for patient recruitment and engaged investigator networks speaks volumes about our expertise in psychiatric trial development and execution.

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Our Team of Neuroscience Functional Experts