Rest Easy with Worldwide Managing Your Sleep Apnea Clinical Trial
The American Sleep Apnea Association estimates that 22 million Americans suffer from sleep apnea, and 80% of the cases of moderate and severe obstructive sleep apnea (OSA) remain undiagnosed. Although OSA is understood to arise from a physical blockage of the airway, the causes of other sleep apneas are undetermined. Centralized sleep apnea (CSA) occurs when the brain does not send signals to stimulate breathing. CSA can occur alongside OSA (complex sleep apnea), but the CSA component of complex sleep apnea can be difficult to detect until the OSA component is identified and treated.
If your team is working on therapies to address the neurological challenges posed by CSA, how will you source appropriate study participants? You’ll need access to clinicians who can help you identify candidates with CSA, and you’ll need to develop testing protocols that will focus on the efficacy of your treatment while monitoring other factors that can influence the course of sleep apnea itself (such as weight gain or weight loss, other comorbid conditions, and more). How will you manage the ethical issues that could arise in the exploration of your therapy? If your participants have complex sleep apnea, you cannot stop treating their OSA while you conduct research into the effectiveness of your therapy on their CSA.
With 30+ years of experience supporting CNS research, Worldwide Clinical Trials is an internationally acclaimed expert in clinical trial management. We offer full-service Phase I–Phase IV and real-world evidence clinical research services for studies into sleep apnea and other diseases affecting the central nervous system. We have long-established relationships both with sleep centers and clinicians that can help you gain insight into the efficacy of the therapy you are developing.